Presentations by 2022 Recipients of CJD Foundation Research Grants:

On Saturday morning, following the Keynote talk, attendees will have the opportunity to hear presentations by 5 of the 10 recipients of 2022 CJD Foundation Research Grants.

In the first segment, Group A (3 speakers) and Group B (3 speakers) will present simultaneously in two different rooms.  You may choose one group to view 3 presentations (as a courtesy to speakers and participants, please do not change rooms during this segment). 

Following the coffee break, Group A (2 speakers) and Group B (2 speakers) will present simultaneously in two different rooms.  Again, please choose one group to view 2 presentations (as a courtesy to speakers and participants, please do not change rooms during this segment). 

All 10 presenters will return to the (Ballroom) for the Question & Answer panels and Moving Roundtables.

While you will only view 5 presentations, all 10 will be recorded and posted on www.cjdfoundation.org at a later date.

To learn about all 10 of the studies, you may view the 5-minute overviews below to decide which presentations you would like to attend.

Group A, Part 1

Leonardo Cortez, PhD & Valerie Sim, MD, FRCPC

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"Prion protein aggregate size distribution drives clinical phenotype"

Cathryn Haigh, PhD

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"Regional tropism of sporadic CJD subtypes in human brain organoids"

Shashirekha Shetty, PhD

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"Examining copy number variants as a possible phenotype modifier in prion disease"

Group B, Part 1

Marcelo Barria, PhD & Alison Green, PhD

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"Assessing the replication properties of prion protein aggregates found in archived formalin-fixed, paraffin embedded appendix tissue collected from the asymptomatic population by the highly sensitive in vitro prion amplification assay"

Joaquín Castilla, PhD

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"Development and characterization of the fastest animal model able to propagate GSS prions faithfully"

Jaime Noguez, PhD

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"Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results"

Group A, Part 2

Hermann Clemens Altmeppen, PhD

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"Enzymatic PrP shedding in humans: Biomarker potential and therapeutic target"

Maria Letizia Barreca, PhD

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"Blocking the Neurotoxic Activities of Mutant Prion Proteins by a Novel Class of Therapeutic Agents"

Group B, Part 2

Zerui Wang, MD, PhD and Katsumi Doh-ura, MD, PhD

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"Assessing Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on CJD"

Rodrigo Morales, PhD

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"Development of a high throughput system for screening anti-prion molecules"