PKU is a rare genetic condition in which a person’s body can't break down an amino acid called phenylalanine. Amino acids are the building blocks of proteins, and phenylalanine is found in most foods. When someone has PKU, phenylalanine builds up in the blood because their body can’t process it quickly enough. Over time, too much phenylalanine can cause brain damage, including developmental delays and neurological symptoms. 

Because it is such a rare disease, the financial support necessary to advance research falls on the families and individuals who care passionately about pursuing a cure; it was this personal dedication that formed National PKU Alliance. With your help, our fundraising efforts will support this critical effort. Seldom has a grassroots effort made such a difference in the treatment of a rare disease. 

National PKU Alliance (NPKUA) is the only national organization dedicated solely to supporting individuals and families affected by phenylketonuria (PKU). NPKUA’s mission is improve the lives of individuals with PKU, pursue a cure by expanding research and provide education and support to individuals living with PKU and their caregivers.

HOW DOES MY DONATION OR FUNDRAISING EFFORTS HELP? 

Funds raised as part of Punch for PKU will go towards supporting the mission of National PKU Alliance, including: 

Community support programs such as our mentorship program community calls and support kits.  

Educational resources for navigating life with PKU, from birth through adulthood.  

Research of exciting new treatments, such as gene therapy, and medical devices, like a home Phe monitor. 

You are at the center of everything we do. Your generosity allows us to keep pushing forward on your behalf. Thank you.