Please help me support Girl Power 2 Cure in their efforts to raise funds for research for Rett Syndrome. This is the 8th year that I have run with Team GP2C in honor of my daughter, Allison. Allison was only 2 years old when she was diagnosed with Rett Syndrome, a genetic disorder that impacts every moment of her life.

Rett Syndrome is a debilitating neurological disorder that predominantly affects females (but can also affect boys). Rett Syndrome is the leading genetic cause of severe neurological impairment in girls and is characterized by a single gene mutation that leads to underproduction of an important brain protein known as MECP2.

Kids are born “normal,” but without the protein, begin to lose acquired skills between 1 and 3 years old. Most lose their ability to speak, walk or use their hands, and depend on their families for every part of their day. Complications also include seizures, scoliosis, and the potential for sudden death.

Despite their physical disabilities, girls and boys with Rett Syndrome function at a similar cognitive level to their peers. Amidst the mass confusion in their central nervous systems, they are smart, strong, and waiting bravely for us to unlock the door to a cure and their recovery. 

Today, there is no cure. But Rett Syndrome is potentially CURABLE! Mouse and primate experimental treatments have proven that once MECP2 protein levels are restored to normal levels, symptoms subside. This past year, Allison was able to participate in a Phase 3 Clinical trial for a promising treatment for Rett Syndrome, the drug trofinetide which is currently being presented to the FDA for approval by the Acadia pharmaceutical company as one of the first treatments for Rett! There are many exciting advancements in Rett Syndrome research, and many of those new discoveries are thanks to generous supporters like you!