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Prion Disease Basics – Clinical

Brian Appleby, MD

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Prion Disease Basics – Research

Joel Watts, PhD

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Bereavement Workshop - Tessa Garcia McEwen, AM, LCSW, DCCS, CDP

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Keynote Address: Novel Mouse Models of Prion Diseases - Glenn Telling, PhD

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Investigation of Glycoprotein Nonmetastatic Melanoma protein B (GPNMB) as potential therapeutic target in Prion Diseases

Elena De Cecco, PhD

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Development of ADAM8-based Gene Therapy for CJD

Qingzhong Kong, PhD

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Understanding the molecular mechanism of spontaneous prion emergence in knock-in mouse models

Surabhi Mehra, PhD, MSc (CJDF Fellowship)

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Bridging the pre-clinical gap for a small brain-penetrant molecule that reduces PrPC levels

Gerold Schmitt-Ulms, PhD

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Exploring the efficacy of dominant negative protein-based gene therapy for different prion diseases: in vivo proof-of-concept study

Joaquín Castilla, PhD

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Generating cerebral organoids from donors with sporadic Creutzfeldt-Jakob Disease

Arielle Hay, PhD (CJDF Fellowship)

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Validation of a non-invasive diagnostic test for prion diseases using tear fluid

Matthias Schmitz, PhD

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A Multi-Targeted Approach in Search of Prion Disease Therapy

James Mastrianni, MD, PhD

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CJD Foundation Report: Programs, Finance, Advocacy, and Strides for CJD - Stuart Yaffa and Jacob Schwister

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CJD Foundation Grants Program - Debbie Yobs and Joel Watts, PhD

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National Prion Disease Pathology Surveillance Center Panel - Brian Appleby, MD, Eriton Cunha, PhD, Katie Glisic, MA, Meghan Lewis, MA, and Gabriella DelPrete

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The 2025 Centers for Disease Control and Prevention Report

Ryan Maddox, PhD

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Drug Development Panel

Kiyoshi Arita, MSc, Project/Product Manager, Research & Development Division, International Clinical Development Department, Nobelpharma Co., Ltd., Tôkyô, Japan

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Anne Smith, PhD, Vice President of Clinical Development, Ionis Pharmaceuticals, Inc., Carlsbad, CA

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Drug Development Panel Question and Answer